X-linked Agammaglobulinemia

Case Study: “X-linked Agammaglobulinemia”

All responses must be in your own words. Answers that have been copied and pasted will not receive credit.

1. Bill was well for the first 10 months of his life. State a plausible explanation for this. Be specific.

2. Based on information in the case study, state one reason why specific immunity diminishes with advancing age.

3. What laboratory test results indicate that Bill has no B-cells?

4. Based on information in the case study, what is Bill’s brother John’s likely diagnosis? Why?

5. Does Bill’s innate immune system appear to be normal? What lab results support your answer?

6. This is the second case study we’ve reviewed that mentions bronchiectasis secondary to repeated bacterial respiratory infections.According to this case study, what is the etiology of the bronchiectasis?

7. What are gamma globulins (as found in plasma)? Where does the name ‘gamma globulin’ originate? [Internet]

8. What is Immune Globulin (as used in intravenous therapy)? [Internet]

9. Name 3 other situations where Immune Globulin is administered. [Internet]

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